RSV vaccine trial shows promising results, Pfizer says; company will seek FDA approval this year

They need to deliver solutions to the Procurement product roadmaps that meet the overall strategic direction for GSK and the GSK overall operating model. Designing strategy, assessing stakeholder impacts and organizational readiness, recommending and / or implementing appropriate communication, and training, and measuring effectiveness to enhance organization, group, and individual performance. This joint venture was the first step in our plan to separate and become two new publicly traded companies, each with the ability to improve the lives of hundreds of millions of people. GSK is one of the world’s foremost pharmaceutical and healthcare companies, and we are proud to be part of an industry that improves the lives of others. J. Craig Venter, the genomics mogul and scientific wizard who recently created a unique living organism from scratch in a matter of days, is searching for pay-dirt in biodiversity-rich marine environments around the world.

Find out whether Pfizer is potentially over or undervalued by checking out our comprehensive analysis, which includes fair value estimates, risks and warnings, dividends, insider transactions and financial health. For seller-fulfilled items from Fine Art category, the sellers need to be informed of the damage / defect within 10 days of delivery. If you do not receive a response from the seller for your return request within two business days, you can submit an A-to-Z Guarantee claim. Return the watch in the original condition in brand box to avoid pickup cancellation.

When corporations do develop a new drug, it more than likely doesn’t provide much value to society. Remarkably, a full 70 percent of the medicine brought to market by the industry in the past 20 years provided no therapeutic benefit over the products already available. Instead, these “me too” drugs were put forward in order to grab a share of an existing lucrative market. When pushing for the TRIPS agreement and other mechanisms to extend medicine patent rights, pharmaceutical corporations justify enclosure by claiming that patents are necessary to spur innovation.

Months later, we were gratified to learn that the authors had elected to retract their paper. In the face of popular articles proclaiming that science is stumbling, this episode was an affirmation that science is self-correcting. In the trial, the vaccine was given to pregnant people and appeared to be about 80% effective at preventing severe RSV disease in their infants in the first three months of life. It also cut a baby’s risk of needing to see a doctor for an RSV infection by half. Against this ominous backdrop, the World Trade Organization in 1986 convened talks to create a global intellectual-property agreement. At the time the talks began, more than 40 of the 90 counties involved refused to grant patents for pharmaceutical products, and others that did grant them adopted strict limits.

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We are targeting the problem of selective outcome reporting in clinical trials. The company trying to be the first to turn the powerful gene-editing tool CRISPR into medicine faces a number of hurdles. Free Credit Score Report: Credit Monitor Not too may people are held accountable for their performance. The operation is so numbers driven that everything else takes a back seat, making it frustrating for conscientious employees.

In other words, it’s ok to post pre-prints so long as nobody noticed the pre-print. That is, they are rather unambiguously not endorsing the point of pre-prints, which is to get your work out to the community more quickly and effectively. One of the things that I think a lot of people coming to the meeting didn’t realize is that many journals are perfectly fine with people posting pre-prints of articles that are being considered by the journal.

Sci-Hub has the potential to encourage and inspire other academics to stand up to the status quo and demand effective reforms, maybe even taking action themselves. Sci-Hub clearly is not how one would design a scholarly infrastructure, but it has been more effective at accomplishing access than anything in the last 20 years. And I think the meeting was highly effective all three regards.

After nine months, we asked the journal why, at minimum, an expression of concern had not been posted. An editor admitted that they had not anticipated the process taking as long as it had. The journal communicated its decision to accept our letter and retract the article 11 months after our submission. We are a group of researchers working on obesity, nutrition and energetics. We and others submitted a letter1 to the editor explaining the problem.

Many proposals are grounded in redirecting the enormous government investment in the current patent system to greater support for early-stage research and prize-oriented funding to motivate late-stage drug development. At varying levels, many of these proposals are already in operation. Last year, US social media and politicians exploded https://1investing.in/ with anger when a young pharmaceutical company executive increased the price of a toxoplasmosis drug by some 5,000 percent overnight. Over a hundred leading US cancer physicians co-authored an article decrying the greed of the pharmaceutical industry, noting that the cost of cancer medicine averages over $100,000 per patient annually.

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On the one hand, they have never scienced without the Internet, and are accustomed to being able to get access to information easily and quickly. On the other hand, they are afraid that the kinds of changes we are pushing will make their lives more difficult, and will make many of the pathologies in the current system worse, especially those biased against them, worse. Even those who have no reservations about the pre-prints and/or post-publication review, don’t feel like they’re in a position to lead the charge. If anything is going to stop the move towards pre-prints, it’s going to be our proclivity for “glamor humping” .

For Android smartphones, our Returns Centre will prompt you to download the Blancco app to diagnose issues with a defective smartphone. We’ll provide a resolution on the basis of the Blancco app diagnostic results. In certain cases, we may also schedule a technician visit to your location. Besides saving lives by making 48 million research papers accessible to patients and doctors, Sci-Hub to me signifies that the scientific community , is starting to lose its patience and becomes ready for more revolutionary reform options. A signal that the community starts to feel that it is running out of options for evolutionary change. To me, Sci-Hub signals that publisher behavior, collectively, over the last two decades has been such a gigantic affront to scholars that civil disobedience is a justifiable escalation.

An external statistical review subsequently commissioned by the journal confirmed the error. The authors were asked to retract the article, but they refused. The journal ultimately posted the authors’ response to our letter and a summary of commissioned reviewers’ criticism.

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The opening night was dominated by a keynote talk from Paul Ginsparg, who in 1991 started an online pre-print server for physics that is now the locus for the initial publishing of essentially all new work in physics, mathematics and some areas of computer science. Paul is a personal hero of mine – for what he did with arXiv and for just being a no bullshit advocate for sanity in science publishing – so I was bummed that he couldn’t make it person because of weather-related travel issues. But his appearance as a giant head on a giant screen by video-conference was a fitting representation for his giant place in pre-print history. His talk was very effective in squashing any of the typical gloom-and-doom about the end of quality science that often happens when pre-prints are discussed.

• However, the right to privacy should not extend to funding arrangements10.
• A petition now circulating for a global research agreement calls on policymakers to “Make Medicines for People, Not Profit.” For that noble goal to be achieved, the fence surrounding essential medicines will need to be torn down once and for all.
• The Alternative R&D Mapping Project documents a range of alternative initiatives catalogued by Universities Allied for Essential Medicines .
• Supported by world-class markets data from Dow Jones and FactSet, and partnering with Automated Insights, MarketWatch Automation brings you the latest, most pertinent content at record speed and with unparalleled accuracy.
• Obviously, the publishers complain that she used her site, Sci-Hub, to ‘steal their content‘ – with their content being of course the knowledge of the world that they have been holding hostage for a gigantic ransom.

I like to see this level of insider ownership, because it increases the chances that management are thinking about the best interests of shareholders. While insider transactions are not the most important thing when it comes to long-term investing, logic dictates you should pay some attention to whether insiders are buying or selling shares. 404 – A John Decker Thriller was published by Cornucopia Press in November 2014. Items that you no longer need must be returned in new and unopened condition with all the original packing, tags, inbox literature, warranty/ guarantee card, freebies and accessories including keys, straps and locks intact. All PC components, listed as Components under “Computers & Accessories” that are labeled as not returnable on the product detail page are not eligible for returns.

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Others, likeEMBO,PNAS,Science and allNature journals unambiguously allow pre-print posting. On the flip side, journals from the American Chemical Society and some other publishers will not accept papers if they were posted as pre-prints. The second day had two sessions, each structured around a series of a dozen or so five minute talks, followed by breakout sessions and then discussion.